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Dr. Ronald Sigal is a Professor of Medicine, Cardiac Sciences, Kinesiology and Community Health Sciences Division of Endocrinology and Metabolism, University of Calgary. Dr. Sigal is a Health Senior Scholar of the Alberta Heritage Foundation for Medical Research.

Dr. Andreas Flouris is a Greek-Canadian Professor of Physiology at the Univ. of Thessaly Dep. of Exercise Science (Greece) and a Visiting Professor in the Faculty of Health Sciences at the Univ. of Ottawa (Canada). He is the Director of FAME Lab, a research facility investigating the (F)unctional (A)rchitecture of (M)ammals in their (E)nvironment.

Dr. Pierre Boulay is a full-time professor in the Faculté de l’acitivité physique et sportive at the Université de Sherbrooke. His work at the University of Sherbrooke involves implementing both a kinesiology clinic and a clinical research program related to the use of physical activity in the management of various health conditions in vulnerable populations.

Dr. Andrew Seely is Professor of Surgery within the Divisions of Thoracic Surgery and Critical Care Medicine at the University of Ottawa, Scientist at the Ottawa Hospital Research Institute, a thoracic surgeon and intensivist at The Ottawa Hospital, Division Head in the Department of Thoracic Surgery at The Ottawa Hospital, Past President of the Canadian Association of Thoracic Surgeons, as well as Founder and Chief Executive Officer of Therapeutic Monitoring Systems Inc.

Dr. Naoto Fujii is currently an Associate Professor at the University of Tsukuba, Japan. His research focuses on elucidating the peripheral mechanisms underlying heat loss responses. He has identified several key factors involved in the regulation of these responses, including nitric oxide synthase, cyclooxygenase, potassium channels, and various hormones.

Dr. Shane Journeay is presently an Assistant Professor in the Department of Medicine at Dalhousie Medicine New Brunswick, Dalhousie University where he is the JD Irving Endowed Chair in Occupational Medicine. He is a specialist in Physical Medicine & Rehabilitation in Canada (FRCPC) and the USA (DABPMR). He is also Board Certified in Occupational Medicine and is a graduate of both the Harvard Occupational & Environmental Residency program and the Harvard School of Public Health.

Dr. Antonia Kaltsatou is a clinical exercise physiologist and researcher specializing in the role of physical activity in the management of chronic diseases, with a particular focus on neurodegenerative disorders such as Multiple Sclerosis and Parkinson’s Disease. She currently serves as an Adjunct Associate Professor at the University of Thessaly in Greece

Dr. Greg McGarr is a Research Scientist with the Consumer and Clinical Radiation Protection Bureau at Health Canada and an Adjunct Professor in the School of Human Kinetics at the University of Ottawa. His current research examines the thermal effects of radiofrequency electromagnetic field (RF-EMF) exposures on the human body.

Dr. Tatsuro Amano is an Associate Professor in the Faculty of Education at Niigata University, Japan. He teaches exercise and human physiology in the physical education program and the Department of Engineering. His research focuses on exercise and environmental physiology.

Dr. Leonidas G. Ioannou is an Assistant Professor at the Jožef Stefan Institute in Slovenia, a Visiting Lecturer at the Medical School of the University of Cyprus, and a Senior Researcher at the University of Thessaly, Greece. His research explores how environmental factors, particularly temperature, affect human health, physiology, sleep, cognition, and occupational performance.

Sean Kidd is a Clinical Psychologist, a Senior Scientist, and the Co-Director of the Institute for Mental Health Policy Research at the Centre for Addiction and Mental Health. He is a Professor in the Psychiatry Department at the University of Toronto. Dr. Kidd's areas of focus have included developing and testing interventions for psychosis populations and for youth who have experienced homelessness. He had also worked extensively in the area of health equity and climate change – with a focus on inadequately housed populations.

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Dr. Ronald Sigal is a Professor of Medicine, Cardiac Sciences, Kinesiology and Community Health Sciences Division of Endocrinology and Metabolism, University of Calgary. Dr. Sigal's current research focuses on clinical trials and cohort studies related to physical activity, obesity, diabetes and cardiovascular disease. He is the principal investigator of four randomized trials evaluating exercise interventions in people with or at risk of diabetes, funded by the Canadian Institutes of Health Research and/or the Canadian Diabetes Association. He was the principal author of the 2006 American Diabetes Association Statement on Physical Activity/Exercise and Diabetes, and headed the writing committee for physical activity guidelines for the Canadian Diabetes association 2003 and 2008 guidelines. Dr. Sigal is a Health Senior Scholar of the Alberta Heritage Foundation for Medical Research.
Most significant contributions pertinent to Dr. Kenny's research (Numbers of citations are on ISI Web of Science as of February 17, 2018):
COLLABORATIVE RESEARCH WITH DR. GLEN KENNY ON EXERCISE AND TEMPERATURE REGULATION IN OLDER PEOPLE AND PEOPLE WITH DIABETES Dr. Kenny and I have jointly authored >80 peer-reviewed publications, including those below. Our work was featured in our invited review “Body temperature regulation in diabetes” (Temperature, Jan 2016).
DIABETES AEROBIC AND RESISTANCE EXERCISE (DARE) TRIAL Sigal RJ, Kenny GP, et al. Effects of aerobic exercise, resistance exercise,or both on glycemic control in type 2 diabetes: a randomized trial. Ann Intern Med 2007;147:357-369. This paper describes the main results of the CIHR-funded DARE trial, of which I was PI. It was the first trial to show aerobic and resistance training each improved glucose control (HbA1c) in type 2 diabetes (T2D), and combined aerobic+resistance exercise was superior to either type of exercise alone. Cited 507 times on ISI Web of Science as of February 17, 2018 (top 1% of 2007 publications). We published 13 other DARE trial papers.
EXERCISE AND TYPE 1 DIABETES (T1D): CHRONIC AND ACUTE EFFECTS OF AEROBIC AND RESISTANCE EXERCISE. We recently concluded the Type 1 Diabetes Aerobic and Resistance Exercise ( T1-DARE) trial in previously-sedentary T1D, and the CIHR-funded Resistance Exercise in Already-active Diabetic Individuals (READI) trial in habitually aerobically active T1D patients. In contrast to T2D, we found neither aerobic nor resistance exercise reduced HbA1c. In separate studies in T1D patients (YardleyJE et al, Diabetes Care 2012 and 2013), we found a 45-min session of resistance exercise caused much less acute drop in blood glucose and hypoglycemia than an aerobic session of the same length. When resistance exercise was performed before aerobic in the same session, there was far less hypoglycemia than if the order was reversed. These studies have key practical implications for active people with T1D.
EXERCISE AND DIABETES: SYSTEMATIC REVIEWS & POSITION STATEMENTS
Boulé, NG, Haddad E, Kenny G, Wells GA, Sigal RJ. Effects of Exercise on HbA1c and Body Mass in Type 2 Diabetes Mellitus: A Systematic Review. JAMA 2001 Sep;286(10):1218-27. Cited 817 times.
Boulé NG, Kenny G, Haddad E, Wells G, Sigal RJ. Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in type 2 diabetes mellitus. Diabetologia Aug 2003 46:1071-1081. Cited 241 times.
Sigal RJ, Kenny GP et al. ADA Statement: Physical Activity/Exercise and Type 2 Diabetes. Diabetes Care 2006 29:1433-38. Cited 454 times.
Exercise trials in T2D published before these papers were small and inconclusive. Our meta-analyses showed exercise improved HbA1c, T2D patients in exercise trials improved aerobic capacity, strength and endurance similarly to non-T2D subjects, and greater intensity of aerobic exercise was associated with greater improvement in HbA1c. In part due to our findings, Clinical Practice Guidelines (CPGs) for exercise in diabetes were changed and levels of evidence upgraded. I was lead author of the 2004 Technical Review and 2006 Position Statement for the American Diabetes Association (ADA), and chapters on Physical Activity/Exercise in the 2003, 2008, 2013 Canadian Diabetes Association (CDA) CPGs. I chaired or co-chaired writing committees for the 2018 Diabetes Canada and 2016 ADA CPGs on exercise.

Dr. Andreas Flouris is a Greek-Canadian Professor of Physiology at the Univ. of Thessaly Dep. of Exercise Science (Greece) and a Visiting Professor in the Faculty of Health Sciences at the Univ. of Ottawa (Canada). At the Univ. of Thessaly, he is also the Chair of the Graduate Program “Military Fitness and Wellbeing”. He also serves as an External Advisory Board Member for the Dep. of Biosystems at KU Leuven in Belgium.
For over 15 years, Prof. Flouris has advised governments and organizations including the Cypriot Presidency, the Greek Ministry of Labour, and the Qatari Ministry of Labour, the World Health Organization, the International Labour Organization, and others on the effects of climate change and environmental factors οn human health, productivity, and wellbeing, as well as impact assessment and risk communication. He has published widely on these topics and has contributed to a series of national and international projects addressing these issues. He is a member of the Advisory Committee on Safety and Health at Work, advising the EU Council on the impacts of environmental factors on safety and health at work. He is a member of the Greek Ministry of Labour Working Group developing measures to address occupational heat stress. Also, he is working with the Asian Development Bank and the Bank of Greece to assess the economic and social impacts of climate change at regional and country level.
Prof. Flouris imagines a world in which everyone understands how the environment impacts their life and plans their activities and goals in harmony with the long-term wellbeing of humanity. He has been recognized in the TIME100 Next list of future global leaders and serves in the VinFuture Prize committee. He is a climate action advocate, and is working with national and international stakeholders to support climate adaptation and actions for a more sustainable world. He is also contributing to efforts translating scientific evidence to environmental, climate, and health policies. He often comments in national and global media, including BBC, CBC, TIME magazine, Financial Times, New York Times, WIRED, El Pais, and the Thomson Reuters Foundation.
Dr. Flouris has mentored over 65 postgraduate researchers: 9 post doctoral researchers, 13 PhD students, and 43 MSc students. He takes pride in their successes and strives to offer them continued support throughout their careers. Early on in his career, he was named Academic All-Canadian Mentor in recognition of his positive impact on students excelling in academics and athletics. He also teaches 3 undergraduate courses as well as 9 graduate courses across 3 Departments at the Univ. of Thessaly.

Dr. Pierre Boulay is currently a full-time professor in the Faculté de l’acitivité physique et sportive at the Université de Sherbrooke.
Dr. Boulay and Dr. Kenny have maintained a long-standing research collaboration (2009-present), which has involved examining the heat stress response in workers and vulnerable population groups (CIHR funded project). Their collaborative efforts have resulted in the publication of 30 articles in highly ranked peer-reviewed journals. These key papers have advanced our understanding of the effect of aging and Type 2 diabetes on the body’s capacity to dissipate heat. They have showed that age-related reductions in whole-body heat loss occurs in adults as young as 40 years (PLoS One 2013,8(12): e83148), which is worsened in sedentary individuals (J Appl Physiol 2015,118(3):299-30), especially those with type 2 diabetes (Med Sci Sports Exerc 2013,45(10):1906-14). Dr. Boulay’s clinical experience over the last 20 years (which includes 20 000+ maximal exercise tests with ECG) in the field of cardiovascular disease (CVD), diabetes, hypertension and obesity has assisted Dr. Kenny with patient screening and assessments for participation in a wide range of research projects. In the future, Dr. Boulay will continue to play an important role in the research at the Human and Environmental Physiology Research Unit by providing regular on-site screening of potential participants and consulting with Dr. Kenny on the suitability of participants for various studies.
After a 10-year absence in academics, Dr. Boulay recently returned as a full-time professor (June 2013) at the University of Sherbrooke where he was recruited for his clinical expertise in exercise physiology. His work at the University of Sherbrooke involves implementing both a kinesiology clinic and a clinical research program related to the use of physical activity in the management of various health conditions in vulnerable populations. During his short tenure (~4 years) as a full-time professor at the University of Sherbrooke, Dr. Boulay has been actively involved in the supervision of 19 MSc trainees as well as 2 PhD trainees. His unique expertise in prescribing exercise to vulnerable populations in view of improving health has attracted many new students to the University of Sherbrooke.
One of Dr. Boulay’s most important research contributions stems from his work as a professor at the University of Moncton (1999-2004) wherein he was conducting work aimed at developing ‘best practices’ related to interventions in cardiac rehabilitation after a myocardial infarction which included an assessment of the related health care costs (Prev Med, 2004,38:586-93). His work lead to the establishment of important clinical predictors for hospital re-admission, healthcare consumption and CVD complications in cardiac patient following a cardiovascular event (Cor Health Care, 2001,5(3):133-40). Furthermore, Dr. Boulay’s work directed at evaluating the impact of beta-blockers on the accuracy of exercise prescription (target heart rate) and the resulting changes on resting metabolic rate and weight loss following an exercise training program (J Card Rehab 2005,25:354-60; Appl Phys Nutr Metab,2007,32(4):664-69; Ob Res,2008,16(9):2088-95) was supported by 2 research grants from the Medical Research Fund of New-Brunswick (2001-02; 2002-03).

Dr. Andrew Seely is Professor of Surgery within the Divisions of Thoracic Surgery and Critical Care Medicine at the University of Ottawa, Scientist at the Ottawa Hospital Research Institute, a thoracic surgeon and intensivist at The Ottawa Hospital, Division Head in the Department of Thoracic Surgery at The Ottawa Hospital, Past President of the Canadian Association of Thoracic Surgeons, as well as Founder and Chief Executive Officer of Therapeutic Monitoring Systems Inc. Dr. Seely’s education includes an undergraduate honors in Physics at Carleton University, followed by medical school, general surgery training, and a doctoral degree in basic science from McGill University, and thoracic surgery and critical care medicine training at the University of Ottawa. Dr Seely’s domains of research interests include: (1) understanding the origins and significance of complex biologic vital sign variability; (2) combining multiorgan variability with predictive modelling to create predictive decision support that help advise doctors regarding a patient’s risk of future deterioration due to infection, risk of extubation failure after separation from a ventilator and more; (3) development and implementation of a systematic means to continuously monitor all adverse events after all thoracic surgery along with novel feedback methods to improve surgical care; and (4) multidisciplinary research exploring the clinical insights of complex systems science (e.g. emergence, uncertainty) and the importance of human entropy production to human health. Dr. Seely has supervised several graduate students, built research teams, published over 240 peer-reviewed papers, presents annually at international meetings and has been awarded over $9M in competitive grant funding. He shares his family life with Kathy Patterson and their daughters Phoebe and Ruby in Ottawa.
The first domain of contribution relevant to Dr. Kenny's research is within the domain of theoretical research exploring clinical applications of complex systems science. Dr. Seely hypothesized that multiorgan variability monitoring may be helpful for diagnosis and prognosis of critical illness (Crit Care Med, 2000); and presented a novel analysis and classification of techniques to characterize variability (Crit Care 2004). Dr. Seely introduced a novel hypothesis for the ubiquitous emergence of fractal structures in time and space, relating to maximal entropy production (Chaos 2012) and then focused on the concept of embracing uncertainty (Persp Biol & Med 2013) and on the vital importance of human entropy production (Entropy, 2023; Entropy 2020, Ann N Y Acad Sci. 2025). Applying these theoretical concepts at the bedside, Dr. Seely pioneered software to analyze waveforms and perform variability analysis of heart and respiratory rate (HRV & RRV), converted variability metrics to predictive models using machine learning, designed software tools with predictive models to be used by clinicians, and founded the commercialization of clinical decision support (CDS) tools to be utilized at the bedside. Research has demonstrated that altered patterns of heart rate variability (HRV) and respiratory rate variability (RRV) are associated with age and illness and that exercise training is capable of improving HRV. Dr. Seely’s research studies include the application of continuous variability monitoring in: 1) the early detection of infection (PLoSOne, 2009; PLoS One, 2012; Transplant Cell Ther. 2021); 2) predicting risk of future deterioration due to infection (Shock, 2019); 3) tracking severity of organ failure (J Crit Care, 2013); 3) prediction of extubation failure (Crit Care, 2014; BMJ Open, 2021; J Intensive Care Med, 2024; BMJ Open, 2025 ); 4) predicting likelihood of donation success following circulatory death (Crit Care Explor 2022; Transplantation Direct 2025); and 5) as a measure of cardiopulmonary fitness and for tracking exercise-induced hyperthermia and thermal strain due to prolonged heat exposure (Appl Physiol Nutr Metab, 2013, 2023, 2024; Eur J App Physiol 2012, 2014, 2020; Exp Physiol, 2019). Building on this research, Dr. Seely has hypothesized that multiscale self-similar fractal structure contained in HRV and RRV is related to the capacity to maximize entropy production, and that health is characterized by robust entropy production at rest combined with the ability to elevate it in response to exercise or heat stress (i.e. both function & adaptability). Dr Seely in collaboration with Drs. Glen Kenny and Andre Longtin (physicist) are pioneering this groundbreaking research (Entropy, 2023; Entropy 2020, Ann N Y Acad Sci. 2025).

Dr. Naoto Fujii is currently an Associate Professor at the University of Tsukuba, Japan. His research focuses on elucidating the peripheral mechanisms underlying heat loss responses. He has identified several key factors involved in the regulation of these responses, including nitric oxide synthase, cyclooxygenase, potassium channels, and various hormones. More recently, his work has expanded to temperature-sensitive ion channels, particularly transient receptor potential (TRP) channels such as TRPV4, TRPV3, TRPA1, TRPM8, and TRPV1.
In addition, Dr. Fujii has been extensively investigating cardiovascular and respiratory control during exercise. Specifically, he has studied hyperthermia-induced hyperventilation in humans, both at rest and during exercise, for more than two decades, publishing numerous significant findings in this area.
At the Institute of Health and Sport Sciences, his laboratory attracts many students interested in sports science, where they conduct physiological and nutritional studies related to various athletic activities, including running, swimming, and team sports.

Dr. Shane Journeay is presently an Assistant Professor in the Department of Medicine at Dalhousie Medicine New Brunswick, Dalhousie University where he is the JD Irving Endowed Chair in Occupational Medicine. He is a specialist in Physical Medicine & Rehabilitation in Canada (FRCPC) and the USA (DABPMR). He is also Board Certified in Occupational Medicine and is a graduate of both the Harvard Occupational & Environmental Residency program and the Harvard School of Public Health. He is originally from Nova Scotia and obtained his MD from Dalhousie Medical School. Prior to medical school, he received B.Sc and Master’s degrees from the University of Ottawa, where he investigated the effects exercise and heat stress on cardiovascular physiology. He subsequently completed a PhD in Toxicology with a focus on nanotechnology at the University of Saskatchewan. He has represented Canada at the International Space University in Strasbourg, France, where he received a Diploma in Space Studies. He serves on the editorial board of the PM&R Journal and the Journal of Occupational Medicine and Toxicology.

Dr. Antonia Kaltsatou is a clinical exercise physiologist and researcher specializing in the role of physical activity in the management of chronic diseases, with a particular focus on neurodegenerative disorders such as Multiple Sclerosis (MS) and Parkinson’s Disease. She currently serves as an Adjunct Associate Professor at the University of Thessaly, where she leads and contributes to research projects examining the interactions between physical activity, environmental conditions, and long-term health outcomes in clinical populations.
Alongside her academic role, Dr. Kaltsatou is the scientific advisor for the Greek Multiple Sclerosis Society, where she develops and implements community-based programs that aim to improve mobility, manage fatigue, and enhance the overall quality of life of individuals living with MS. Her work bridges the gap between academic research and real-world applications, ensuring evidence-based interventions reach the communities that need them most.
Her scholarly output includes > 40 peer-reviewed manuscripts indexed in PubMed, addressing critical topics such as heat exposure, exercise-induced thermoregulation, aging and physiology, and the impact of environmental stressors on health and physical performance. Dr. Kaltsatou has successfully secured competitive research funding and has been recognized at the national level for her outstanding contributions to the field of MS research. Her current research includes investigating the impact of multidisciplinary rehabilitation programs on the functional and psychological well-being of individuals with MS. Her long-term vision is to ensure that exercise training guidelines for people with chronic diseases, especially MS, explicitly account for environmental conditions such as heat, humidity, and access to cooling strategies. By improving the scientific understanding of how these factors interact with physical activity, she aims to develop practical, evidence-based interventions that can be safely implemented in daily life. Ultimately, her work seeks to empower individuals with MS to remain active, manage symptoms more effectively, and improve their overall quality of life through personalized and environmentally adapted exercise programs.

Dr. Greg McGarr is a Research Scientist with the Consumer and Clinical Radiation Protection Bureau at Health Canada and an Adjunct Professor in the School of Human Kinetics at the University of Ottawa. He previously completed a BSc in Health Sciences (Brock University), an MSc in Medical Biophysics (University of Western Ontario), and a PhD in Applied Health Sciences (Brock University) in the field of Environmental Ergonomics. He then spent three years as a Postdoctoral Fellow with the Human and Environmental Physiology Research Unit (HEPRU) at the University of Ottawa studying the physiology and pharmacology of skin blood flow and sweating in healthy and clinical populations. He continues to collaborate with Dr. Kenny on related projects and in HEPRU’s ongoing research examining physiological and perceptual responses of older adults to indoor overheating.
Greg’s current research with Health Canada examines the thermal effects of radiofrequency electromagnetic field (RF-EMF) exposures on the human body. His research program involves a combination of in vitro studies in primary human keratinocytes exposed to direct heating and RF-EMFs as well as in vivo studies of human skin responses to contact heating and localized RF-EMF exposures. His work is funded by Health Canada, the Natural Sciences and Engineering Research Council of Canada, and the Government of Canada’s Genomics Research and Development Initiative. In addition to his research work, he also serves as an advisor to the World Health Organization as a member of the Task Group on Radiofrequency Fields and Health.

Dr. Tatsuro Amano is an Associate Professor in the Faculty of Education at Niigata University, Japan. He teaches exercise and human physiology in the physical education program and the Department of Engineering. His research focuses on exercise and environmental physiology, with a particular emphasis on sweating and cutaneous vascular responses across systemic to peripheral (pharmacological) levels, as well as the integration of transdermal drug delivery systems in humans.

Dr. Leonidas G. Ioannou is an Assistant Professor at the Jožef Stefan Institute in Slovenia, a Visiting Lecturer at the Medical School of the University of Cyprus, and a Senior Researcher at the University of Thessaly, Greece. He holds undergraduate degrees in Exercise Physiology (BSc) and Health Sciences (BHSc), a Master of Science (MSc) in Exercise and Health, and two PhDs in Environmental and Occupational Physiology from the University of Thessaly, Greece, and the University of Copenhagen, Denmark. He also completed a full year of advanced academic training in thermophysiological modeling at the University of Porto, Portugal. In recognition of his research in environmental physiology, he earned the postdoctoral title of Habilitation in Physiology from the Jožef Stefan International Postgraduate School, Slovenia, following a formal academic evaluation.
His research explores how environmental factors, particularly temperature, affect human health, physiology, sleep, cognition, and occupational performance. He has published over 80 peer-reviewed scientific papers and served on several academic and professional committees. Leonidas has participated in numerous European and international research projects, conducting field and laboratory studies across multiple countries, which have contributed to the development of national and international health and safety policies. He collaborates extensively with leading organizations, including the World Health Organization (WHO), the International Labour Organization (ILO), the European Space Agency (ESA), and various European ministries, on initiatives aimed at improving human health and wellbeing.