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    • Dr. Glen Kenny
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    • How hot is the human body
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    • Heat and cell function
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Individual differences in thermoregulatory function

Heat strain in children during unstructured outdoor physical activity in a continental summer climate. McGarr GW, Saci S, King KE, Topshee S, Richards BJ, Gemae MR, McCourt ER, Kenny GP. Temperature (Austin). 2020 Aug 12;8(1):80-89. doi: 10.1080/23328940.2020.1801120.

PMID: 33553507 Free PMC article.

https://pubmed.ncbi.nlm.nih.gov/33553507/


Do sex differences in thermoregulation pose a concern for female athletes preparing for the Tokyo Olympics? Notley SR, Racinais S, Kenny GP.

Br J Sports Med. 2020 Oct 1:bjsports-2020-102911. doi: 10.1136/bjsports-2020-102911. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/33004404/


Ageing attenuates the effect of extracellular hyperosmolality on whole-body heat exchange during exercise-heat stress. Meade RD, Notley SR, Rutherford MM, Boulay P, Kenny GP.

J Physiol. 2020 Sep 29. doi: 10.1113/JP280132. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/32996159/


Impact of uncomplicated controlled hypertension on thermoregulation during exercise-heat stress. Akerman AP, Notley SR, Sigal RJ, Boulay P, Ruzicka M, Friesen BJ, Kenny GP.

J Hum Hypertens. 2020 Oct 14. doi: 10.1038/s41371-020-00402-6. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/33057176/


Effect of aerobic fitness on the relation between age and whole-body heat exchange during exercise-heat stress: a retrospective analysis. Notley SR, Meade RD, Kenny GP.

Exp Physiol. 2020 Jul 1. doi: 10.1113/EP088783. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/32613639/


Evidence for age-related differences in heat acclimatisation responsiveness.

Notley SR, Meade RD, Akerman AP, Poirier MP, Boulay P, Sigal RJ, Flouris AD, Kenny GP.

Exp Physiol. 2020 Jun 27. doi: 10.1113/EP088728. Online ahead of print.

https://pubmed.ncbi.nlm.nih.gov/32592411/


 The Relation between Age and Sex on Whole-Body Heat Loss during Exercise-Heat Stress. D'Souza AW, Notley SR, Kenny GP. Med Sci Sports Exerc. 2020 Apr 20. doi: 10.1249/MSS.0000000000002373. Online ahead of print. PMID: 32496737

 https://pubmed.ncbi.nlm.nih.gov/32496737/ 


Exercise Heat Stress in Patients With and Without Type 2 Diabetes.

Notley SR, Poirier MP, Sigal RJ, D'Souza A, Flouris AD, Fujii N, Kenny GP. JAMA. 2019 Oct 8;322(14):1409-1411. doi: 10.1001/jama.2019.10943.PMID: 31593261 

 https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2019.10943 

 

Whole‐body heat exchange in black‐African and Caucasian men during exercise eliciting matched heat‐loss requirements in dry heat. Muia, CM, Notley, SR, Saci, S, D'Souza, AW, Kenny, GP. Experimental Physiology. 2019; 1-6. https://www.ncbi.nlm.nih.gov/pubmed/31628699


Intermittent sequential pneumatic compression does not enhance whole-body heat loss in elderly adults during extreme heat exposure. D'Souza AW, Notley SR, Meade RD, Kenny GP. Appl Physiol Nutr Metab. 2019 Aug 9. doi: 10.1139/apnm-2019-0364. [Epub ahead of print]

 https://www.ncbi.nlm.nih.gov/pubmed/31398291 


Revisiting the influence of individual factors on heat exchange during exercise in dry heat using direct calorimetry. Notley SR, Lamarche DT, Meade RD, Flouris AD, Kenny GP.

Exp Physiol. 2019 Jul;104(7):1038-1050. doi: 10.1113/EP087666. Epub 2019 May 6.

 https://www.ncbi.nlm.nih.gov/pubmed/30997941 


Impaired whole-body heat loss in type 1 diabetes during exercise in the heat: a cause for concern? Notley SR, Poirier MP, Yardley JE, Sigal RJ, Kenny GP. Diabetologia. 2019 Jun;62(6):1087-1089. doi: 10.1007/s00125-019-4858-5. Epub 2019 Apr 2. 

 https://www.ncbi.nlm.nih.gov/pubmed/30941449 


Menstrual cycle phase does not modulate whole body heat loss during exercise in hot, dry conditions. Notley SR, Dervis S, Poirier MP, Kenny GP. J Appl Physiol (1985). 2019 Feb 1;126(2):286-293. doi: 10.1152/japplphysiol.00735.2018. Epub 2018 Nov 29.: https://www.ncbi.nlm.nih.gov/pubmed/30496713


Interactive effects of age and hydration state on human thermoregulatory function during exercise in hot-dry conditions. Meade RD, Notley SR, D'Souza AW, Dervis S, Boulay P, Sigal RJ, Kenny GP. Acta Physiol (Oxf). 2018 Nov 27:e13226. doi: 10.1111/apha.13226. [Epub ahead of print]:

 https://www.ncbi.nlm.nih.gov/pubmed/30480873


Self-reported physical activity level does not alter whole-body total heat loss independently of aerobic fitness in young adults during exercise in the heat. Lamarche DT, Notley SR, Poirier MP, Kenny GP. Appl Physiol Nutr Metab. 2019 Jan;44(1):99-102. doi: 10.1139/apnm-2018-0211. Epub 2018 Jul 31.: https://www.ncbi.nlm.nih.gov/pubmed/30063161


Screening criteria for increased susceptibility to heat stress during work or leisure in hot environments in healthy individuals aged 31-70 years. Flouris AD, McGinn R, Poirier MP, Louie JC, Ioannou LG, Tsoutsoubi L, Sigal RJ, Boulay P, Hardcastle SG, Kenny GP. Temperature (Austin). 2017 Dec 18;5(1):86-99. doi: 10.1080/23328940.2017.1381800. eCollection 2018.:

 https://www.ncbi.nlm.nih.gov/pubmed/29687046


Fitness-related differences in the rate of whole-body total heat loss in exercising young healthy women are heat-load dependent. Lamarche DT, Notley SR, Poirier MP, Kenny GP. Exp Physiol. 2018 Mar 1;103(3):312-317. doi: 10.1113/EP086752. Epub 2018 Jan 19.: https://www.ncbi.nlm.nih.gov/pubmed/29250845


Fitness-related differences in the rate of whole-body evaporative heat loss in exercising men are heat-load dependent. Lamarche DT, Notley SR, Louie JC, Poirier MP, Kenny GP. Exp Physiol. 2018 Jan 1;103(1):101-110. doi: 10.1113/EP086637. Epub 2017 Nov 22.: https://www.ncbi.nlm.nih.gov/pubmed/29052285


Aging Impairs Whole-Body Heat Loss in Women under Both Dry and Humid Heat Stress. Notley SR, Poirier MP, Hardcastle SG, Flouris AD, Boulay P, Sigal RJ, Kenny GP. Med Sci Sports Exerc. 2017 Nov;49(11):2324-2332. doi: 10.1249/MSS.0000000000001342.: https://www.ncbi.nlm.nih.gov/pubmed/29045327


Increasing age is a major risk factor for susceptibility to heat stress during physical activity. McGinn R, Poirier MP, Louie JC, Sigal RJ, Boulay P, Flouris AD, Kenny GP. Appl Physiol Nutr Metab. 2017 Nov;42(11):1232-1235. doi: 10.1139/apnm-2017-0322. Epub 2017 Aug 24.: https://www.ncbi.nlm.nih.gov/pubmed/28750177


Hyperthermia and cardiovascular strain during an extreme heat exposure in young versus older adults. Kenny GP, Poirier MP, Metsios GS, Boulay P, Dervis S, Friesen BJ, Malcolm J, Sigal RJ, Seely AJ, Flouris AD. Temperature (Austin). 2016 Aug 31;4(1):79-88. doi: 10.1080/23328940.2016.1230171. eCollection 2017.: https://www.ncbi.nlm.nih.gov/pubmed/28349096


Local versus whole-body sweating adaptations following 14 days of traditional heat acclimation. Poirier MP, Gagnon D, Kenny GP. Appl Physiol Nutr Metab. 2016 Aug;41(8):816-24. doi: 10.1139/apnm-2015-0698. Epub 2016 Mar 24.: https://www.ncbi.nlm.nih.gov/pubmed/27467216


Increased Air Velocity Reduces Thermal and Cardiovascular Strain in Young and Older Males during Humid Exertional Heat Stress. Wright Beatty HE, Hardcastle SG, Boulay P, Flouris AD, Kenny GP. J Occup Environ Hyg. 2015;12(9):625-34. doi: 10.1080/15459624.2015.1029613.: 

https://www.ncbi.nlm.nih.gov/pubmed/25897617


Preservation of cognitive performance with age during exertional heat stress under low and high air velocity. Wright Beatty HE, Keillor JM, Hardcastle SG, Boulay P, Kenny GP. Biomed Res Int. 2015;2015:619103. doi: 10.1155/2015/619103. Epub 2015 Mar 22.: https://www.ncbi.nlm.nih.gov/pubmed/25874223


At what level of heat load are age-related impairments in the ability to dissipate heat evident in females? Stapleton JM, Poirier MP, Flouris AD, Boulay P, Sigal RJ, Malcolm J, Kenny GP. PLoS One. 2015 Mar 19;10(3):e0119079. doi: 10.1371/journal.pone.0119079. eCollection 2015.:

 https://www.ncbi.nlm.nih.gov/pubmed/25790024


Aging impairs heat loss, but when does it matter? Stapleton JM, Poirier MP, Flouris AD, Boulay P, Sigal RJ, Malcolm J, Kenny GP. J Appl Physiol (1985). 2015 Feb 1;118(3):299-309. doi: 10.1152/japplphysiol.00722.2014. Epub 2014 Dec 11.: https://www.ncbi.nlm.nih.gov/pubmed/25505030


Older firefighters are susceptible to age-related impairments in heat dissipation. Kenny GP, Larose J, Wright-Beatty HE, Boulay P, Sigal RJ, Flouris AD. Med Sci Sports Exerc. 2015 Jun;47(6):1281-90. doi: 10.1249/MSS.0000000000000537.: https://www.ncbi.nlm.nih.gov/pubmed/25290744


Whole-body heat exchange during heat acclimation and its decay. Poirier MP, Gagnon D, Friesen BJ, Hardcastle SG, Kenny GP. Med Sci Sports Exerc. 2015 Feb;47(2):390-400. doi: 10.1249/MSS.0000000000000401.:

 https://www.ncbi.nlm.nih.gov/pubmed/24870585


Age-related differences in heat loss capacity occur under both dry and humid heat stress conditions. Larose J, Boulay P, Wright-Beatty HE, Sigal RJ, Hardcastle S, Kenny GP. J Appl Physiol (1985). 2014 Jul 1;117(1):69-79. doi: 10.1152/japplphysiol.00123.2014. Epub 2014 May 8.: 

https://www.ncbi.nlm.nih.gov/pubmed/24812643


Do older adults experience greater thermal strain during heat waves? Stapleton JM, Larose J, Simpson C, Flouris AD, Sigal RJ, Kenny GP. Appl Physiol Nutr Metab. 2014 Mar;39(3):292-8. doi: 10.1139/apnm-2013-0317. Epub 2013 Sep 16.: https://www.ncbi.nlm.nih.gov/pubmed/24552369


Moderate-intensity intermittent work in the heat results in similar low-level dehydration in young and older males. Wright HE, Larose J, McLellan TM, Hardcastle SG, Boulay P, Kenny GP. J Occup Environ Hyg. 2014;11(3):144-53. doi: 10.1080/15459624.2013.817676.: https://www.ncbi.nlm.nih.gov/pubmed/24521064


Age-related decrements in heat dissipation during physical activity occur as early as the age of 40. Larose J, Boulay P, Sigal RJ, Wright HE, Kenny GP. PLoS One. 2013 Dec 12;8(12):e83148. doi: 10.1371/journal.pone.0083148. eCollection 2013.: https://www.ncbi.nlm.nih.gov/pubmed/24349447


Whole body heat loss is reduced in older males during short bouts of intermittent exercise. Larose J, Wright HE, Stapleton J, Sigal RJ, Boulay P, Hardcastle S, Kenny GP. Am J Physiol Regul Integr Comp Physiol. 2013 Sep 15;305(6):R619-29. doi: 10.1152/ajpregu.00157.2013. Epub 2013 Jul 24.: https://www.ncbi.nlm.nih.gov/pubmed/23883671


Do older females store more heat than younger females during exercise in the heat? Larose J, Wright HE, Sigal RJ, Boulay P, Hardcastle S, Kenny GP. Med Sci Sports Exerc. 2013 Dec;45(12):2265-76. doi: 10.1249/MSS.0b013e31829d24cc.: https://www.ncbi.nlm.nih.gov/pubmed/23715429


Does sex have an independent effect on thermoeffector responses during exercise in the heat? Gagnon D, Kenny GP. J Physiol. 2012 Dec 1;590(23):5963-73. doi: 10.1113/jphysiol.2012.240739. Epub 2012 Oct 8. Review.: https://www.ncbi.nlm.nih.gov/pubmed/23045336


Sex differences in thermoeffector responses during exercise at fixed requirements for heat loss. Gagnon D, Kenny GP. J Appl Physiol (1985). 2012 Sep 1;113(5):746-57. doi: 10.1152/japplphysiol.00637.2012. Epub 2012 Jul 12.: https://www.ncbi.nlm.nih.gov/pubmed/22797311


Sex modulates whole-body sudomotor thermosensitivity during exercise. Gagnon D, Kenny GP. J Physiol. 2011 Dec 15;589(Pt 24):6205-17. doi: 10.1113/jphysiol.2011.219220. Epub 2011 Oct 17.:

 https://www.ncbi.nlm.nih.gov/pubmed/22005684


Short-term exercise training does not improve whole-body heat loss when rate of metabolic heat production is considered. Stapleton J, Gagnon D, Kenny GP. Eur J Appl Physiol. 2010 Jun;109(3):437-46. doi: 10.1007/s00421-010-1380-3. Epub 2010 Feb 7.: https://www.ncbi.nlm.nih.gov/pubmed/20140682


Heat balance and cumulative heat storage during exercise performed in the heat in physically active younger and middle-aged men. Kenny GP, Gagnon D, Dorman LE, Hardcastle SG, Jay O. Eur J Appl Physiol. 2010 May;109(1):81-92. doi: 10.1007/s00421-009-1266-4. Epub 2009 Nov 3.:

 https://www.ncbi.nlm.nih.gov/pubmed/19885672


Heat stress in older individuals and patients with common chronic diseases. Kenny GP, Yardley J, Brown C, Sigal RJ, Jay O. CMAJ. 2010 Jul 13;182(10):1053-60. doi: 10.1503/cmaj.081050. Epub 2009 Aug 24. Review. No abstract available. : https://www.ncbi.nlm.nih.gov/pubmed/19703915


Core temperature differences between males and females during intermittent exercise: physical considerations. Gagnon D, Dorman LE, Jay O, Hardcastle S, Kenny GP. Eur J Appl Physiol. 2009 Feb;105(3):453-61. doi: 10.1007/s00421-008-0923-3. Epub 2008 Nov 19.: https://www.ncbi.nlm.nih.gov/pubmed/19018561


Sex-related differences in evaporative heat loss: the importance of metabolic heat production. Gagnon D, Jay O, Lemire B, Kenny GP. Eur J Appl Physiol. 2008 Nov;104(5):821-9. doi: 10.1007/s00421-008-0837-0. Epub 2008 Aug 2.: https://www.ncbi.nlm.nih.gov/pubmed/18677506


Sex differences in postexercise esophageal and muscle tissue temperature response. Kenny GP, Jay O. Am J Physiol Regul Integr Comp Physiol. 2007 Apr;292(4):R1632-40. Epub 2006 Nov 30.: 

https://www.ncbi.nlm.nih.gov/pubmed/17138725



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